10 Best AI Medical Billing Software Shortlist
AI medical billing software uses artificial intelligence to automate coding, claims submission, payment posting, and denial management for healthcare organizations. If you’re looking for ways to reduce manual work, minimize errors, and keep up with ever-changing billing rules, these tools are designed for you. With staffing challenges and tighter margins, finding the right AI billing system can make a real difference in your revenue cycle and your team’s day-to-day workload. This guide reviews the top AI medical billing solutions so you can compare features and quickly find the best fit for your needs this year.
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Best AI Medical Billing Software Summary
This comparison chart summarizes pricing details for my top AI medical billing software selections to help you find the best one for your budget and practice needs.
| Tool | Best For | Trial Info | Price | ||
|---|---|---|---|---|---|
| 1 | Best for AI-driven billing accuracy | Free demo available | Pricing upon request | Website | |
| 2 | Best for integrated EHR and practice management | Free demo available | Pricing upon request | Website | |
| 3 | Best for simplifying complex billing procedures | Free demo available | From $199/user/month | Website | |
| 4 | Best for small to mid-sized practices | Free demo available | Pricing upon request | Website | |
| 5 | Best for comprehensive revenue cycle management | Free demo available | Pricing upon request | Website | |
| 6 | Best for AI-driven medical billing | Free demo available | Pricing upon request | Website | |
| 7 | Best for advanced patient accounting features | Free consultation available | Pricing upon request | Website | |
| 8 | Best for Mac users seeking intuitive design | 30-day free trial + free demo available | From $5/user/month | Website | |
| 9 | Best for interoperability and flexibility | Not available | From $75/user/month. | Website | |
| 10 | Best for ophthalmology, neurology, urology specialties | Not available | Pricing upon request | Website |
Best AI Medical Billing Software Reviews
Below are my detailed summaries of the best AI medical billing software that made it onto my shortlist. My reviews offer a detailed look at the features, capabilities, and integrations of each platform to help you find the best one for you.
NextGen is a cloud-based EHR and practice management platform that combines specialty-specific clinical workflows, billing automation, mobile access, patient engagement, and clearinghouse services.
Who Is NextGen Best For?
NextGen works well for specialty care practices that need integrated clinical, billing, and administrative tools with configurable workflows.
Why I Picked NextGen
I picked NextGen because its AI-assisted billing and documentation tools can help practices reduce manual work and improve claims accuracy. Its coding capabilities can suggest ICD-10 codes, lab orders, and charge capture actions based on structured clinical notes. NextGen also offers specialty-specific templates and reporting tools that connect financial performance with patient care, making it a strong option for practices that need automation without sacrificing customization.
NextGen Key Features
- AI-assisted billing: Support coding, charge capture, and claims workflows with automated recommendations based on clinical documentation.
- Claims management: Use rules-based claims scrubbing, eligibility verification, and an integrated clearinghouse to reduce billing errors.
- Specialty-specific templates: Configure documentation and workflows for 26 medical specialties.
- Ambient clinical documentation: Convert provider-patient conversations into structured notes with review and confirmation workflows.
NextGen Integrations
NextGen connects with healthcare applications such as Relaymed, Medsender, Klara, Surgimate, Transform9, CallMyDoc, rater8, and Arcadia. These integrations extend laboratory workflows, patient communication, surgical coordination, analytics, reputation management, and other specialty functions.
Pros and Cons
Pros:
- Secure AWS cloud hosting and mobile EHR access
- Built-in clearinghouse and RCM services
- AI-assisted billing and coding suggestions
Cons:
- Pricing is not published publicly
- May require training to configure workflows
CharmHealth is a cloud-based healthcare platform that combines electronic health records, medical billing, practice management, telehealth, and patient engagement tools.
Who Is CharmHealth Best For?
CharmHealth works well for small to mid-sized healthcare practices that want to manage clinical, financial, and administrative workflows within one connected platform.
Why I Picked CharmHealth
I picked CharmHealth because it brings EHR, billing, scheduling, and patient engagement tools together in one system. This unified approach helps practices manage the patient journey from appointment booking and clinical documentation through claims and payment collection. Its flexible modules and cloud-based design also make it a practical option for organizations that want an integrated platform without relying on multiple disconnected applications.
CharmHealth Key Features
- Integrated medical billing: Manage claims, payments, insurance information, and billing reports alongside clinical records.
- Electronic health records: Document visits, maintain patient histories, manage orders, and support care workflows.
- Patient portal: Give patients secure access to appointments, records, messages, forms, and billing information.
- Telehealth: Conduct virtual appointments while keeping visit details connected to the patient chart.
CharmHealth Integrations
CharmHealth connects its EHR, practice management, billing, telehealth, and patient engagement modules within one ecosystem. It also supports integrations with laboratories, pharmacies, clearinghouses, payment services, and other healthcare applications to extend clinical and administrative workflows.
Pros and Cons
Pros:
- Competitive pricing
- Comprehensive set of features, including a patient portal
- Integrated EHR and practice management
Cons:
- Limited options for third-party integrations
- The user interface may take time to learn
EZClaim is a medical billing and scheduling software designed to streamline complex billing procedures. Its primary function is to automate and simplify these procedures, which typically makes it best for users who want to uncomplicate their billing processes.
Why I Picked EZClaim: I picked EZClaim for this list due to its comprehensive suite of tools that are purposefully designed to simplify intricate billing processes. The ability of this software to make complex procedures more manageable sets it apart from other similar tools. I judge that EZClaim is the best for simplifying complex billing procedures as it offers a balance of user-friendliness with sophisticated functionality.
Standout features & integrations:
Features include simplifying complex tasks via automated claim entry, comprehensive reporting, and patient statement processing.
Integrations include several electronic health records (EHR) systems, enhancing its functionality and making data management easier for users.
Pros and Cons
Pros:
- Extensive features such as automated claim entry and comprehensive reporting
- Key integrations with various EHR systems
- Intuitive design that simplifies complex billing procedures
Cons:
- Lacks a free trial for users to test before purchasing
- The user interface might seem outdated to some users
- The starting price is relatively high compared to other options
Kareo Billing is a cloud-based medical billing platform that helps healthcare practices manage claims, patient payments, financial reporting, and revenue cycle workflows.
Who Is Kareo Billing Best For?
Kareo Billing works well for small to mid-sized medical practices that need scalable billing tools that can support growing claim volumes and administrative demands.
Why I Picked Kareo Billing
I picked Kareo Billing because it combines an accessible interface with billing tools designed for independent practices. Its claim scrubbing, reporting, and patient collection features can help reduce errors, improve payment tracking, and support healthier revenue performance. The platform can also scale as a practice adds providers, patients, or locations, making it a practical choice for organizations that expect their billing needs to grow over time.
Kareo Billing Key Features
- Claims scrubbing: Review claims for coding, demographic, and payer-related errors before submission.
- Billing analytics: Track claims, payments, denials, collections, and other financial performance indicators.
- Patient collections: Manage patient balances, statements, payment activity, and collection workflows.
- Revenue cycle management: Support claims submission, payment posting, follow-ups, and financial reporting from one platform.
Kareo Billing Integrations
Kareo Billing connects with supported EHR and practice management systems to synchronize patient, appointment, and billing information. These integrations help reduce duplicate data entry and keep financial workflows aligned with clinical records.
Pros and Cons
Pros:
- Robust integrations with EHRs and practice management systems
- Scalable for small to mid-sized practices
- User-friendly interface
Cons:
- No free trial available
- The initial setup can be complex
CollaborateMD is a cloud-based medical billing and practice management platform that supports claims processing, eligibility verification, patient payments, and revenue cycle workflows.
Who Is CollaborateMD Best For?
CollaborateMD works well for medical practices and billing teams that need an end-to-end platform for managing claims, payments, and other revenue cycle tasks.
Why I Picked CollaborateMD
I picked CollaborateMD because it covers multiple stages of the revenue cycle, from insurance eligibility checks and claim preparation to payment collection and financial reporting. Its claims scrubbing tools can help practices identify errors before submission, reducing avoidable denials and payment delays. This makes CollaborateMD a strong option for organizations that want to manage billing workflows through one connected system.
CollaborateMD Key Features
- Real-time eligibility verification: Check patient insurance coverage before visits or claim submission.
- Claims scrubbing: Review claims for coding, demographic, and payer-related errors before sending them.
- Patient payment portal: Let patients review balances and make online payments through a secure portal.
- Revenue cycle reporting: Track claims, payments, denials, and financial performance through reporting tools.
CollaborateMD Integrations
CollaborateMD connects with supported EHR and practice management platforms to transfer patient, appointment, and billing information between systems. These integrations help reduce duplicate data entry and keep financial workflows aligned with clinical records.
Pros and Cons
Pros:
- Real-time eligibility checking
- Robust claim scrubbing capability
- Comprehensive revenue cycle management
Cons:
- No free trial available
- Higher entry price compared to other tools
AllegianceMD is a medical billing and practice management platform that uses automation to support coding, claims processing, payment follow-ups, and broader revenue cycle workflows.
Who Is AllegianceMD Best For?
AllegianceMD works well for healthcare practices that want to automate repetitive billing tasks and manage clinical and financial workflows within one connected system.
Why I Picked AllegianceMD
I picked AllegianceMD because its automated billing tools can help practices identify coding issues, review claims before submission, and follow up on outstanding balances. By connecting these functions with patient records and practice management workflows, the platform can reduce manual administrative work and improve billing consistency. This makes AllegianceMD a strong option for practices seeking more automation across the revenue cycle.
AllegianceMD Key Features
- Automated claims scrubbing: Review claims for coding, demographic, and payer-related errors before submission.
- Code checking: Check billing codes against documented services to help improve claim accuracy.
- Automated follow-ups: Track unpaid claims and support follow-up workflows for outstanding reimbursements.
- Integrated revenue cycle management: Manage claims, payments, billing records, and financial reporting within the platform.
AllegianceMD Integrations
AllegianceMD connects its medical billing tools with its EHR and practice management capabilities, helping clinical documentation flow into coding and claims workflows. It also supports connections with laboratories, pharmacies, clearinghouses, and other healthcare services.
Pros and Cons
Pros:
- Automated follow-ups
- Smooth integration with EHR systems and practice management software
- AI-driven features for improved efficiency
Cons:
- Complexity of AI-driven features may have a steep learning curve
- Higher starting price compared to other tools
Medisoft is a medical billing and practice management platform that helps healthcare organizations manage patient accounts, charges, payments, claims, and financial reporting.
Who Is Medisoft Best For?
Medisoft works well for medical practices and billing teams that need detailed patient accounting tools for tracking balances, payments, charges, and insurance activity.
Why I Picked Medisoft
I picked Medisoft because its patient accounting capabilities provide a detailed view of each patient’s financial activity. Billing teams can track outstanding balances, enter charges, post payments, and review account histories from one system. This makes Medisoft a strong option for practices that need greater control over patient accounts and day-to-day financial workflows.
Medisoft Key Features
- Patient account management: Track balances, charges, payments, adjustments, and insurance activity for each patient.
- Charge entry: Record billable services and connect them with the appropriate patient and provider information.
- Payment posting: Apply insurance and patient payments to outstanding balances while maintaining accurate account records.
- Billing and financial reporting: Review claims, collections, aging balances, and other revenue cycle metrics.
Medisoft Integrations
Medisoft connects with supported EHR and clinical documentation systems to transfer patient demographics, charges, and billing information. These integrations help keep financial records aligned with clinical workflows and reduce duplicate data entry.
Pros and Cons
Pros:
- Streamlined financial management
- Integrates with major EHR systems
- Robust patient accounting features
Cons:
- Lack of a mobile application
- May be complex for new users
Billings Pro is a time-tracking, project management, and invoicing platform designed for Apple users. It helps independent professionals and small businesses track billable work, create invoices, and monitor project progress across Mac, iPhone, and iPad.
Who Is Billings Pro Best For?
Billings Pro works well for solo professionals and small service-based businesses that use Apple devices and need straightforward time tracking and invoicing tools.
Why I Picked Billings Pro
I picked Billings Pro because its clean interface and Apple-focused design make it easy to manage billable hours, projects, expenses, and invoices across multiple devices. Users can record time on a Mac, review project activity on an iPhone, and access billing information from an iPad. This makes Billings Pro a practical option for Apple users who prioritize simplicity and device synchronization.
Billings Pro Key Features
- Time tracking: Record billable hours by client, project, or task to support accurate invoicing.
- Invoice generation: Create and send professional invoices based on tracked time, expenses, and project activity.
- Project management: Monitor project progress, budgets, deadlines, and outstanding work from one interface.
- Expense tracking: Record reimbursable costs and add them to client invoices when needed.
Billings Pro Integrations
Billings Pro synchronizes data across supported Apple devices, including Mac, iPhone, and iPad. Its Apple-focused ecosystem allows users to manage time, projects, and invoices across devices, although it does not provide the claims, insurance, coding, or healthcare compliance capabilities of dedicated medical billing software.
Pros and Cons
Pros:
- Robust features including time tracking and invoicing
- Smooth integration across Apple devices
- User-friendly design tailored for Mac users
Cons:
- The annual billing might not be suitable for all users
- Might not be the best fit for non-Mac users
Visolve Medical Billing Module is a healthcare billing solution designed to manage coding, insurance claims, eligibility verification, and financial reporting while supporting connections with existing clinical systems.
Who Is Visolve Medical Billing Module Best For?
Visolve Medical Billing Module works well for healthcare practices that need a flexible billing system capable of adapting to different workflows and integrating with existing EHR and practice management platforms.
Why I Picked Visolve Medical Billing Module
I picked Visolve Medical Billing Module because its flexible architecture supports varied billing workflows and interoperability requirements. Practices can use it to verify insurance eligibility, check codes, process claims, and monitor financial performance without replacing their existing clinical systems. This makes it a strong option for organizations seeking an adaptable billing platform that can evolve alongside operational needs.
Visolve Medical Billing Module Key Features
- Insurance eligibility verification: Check patient coverage before services are provided or claims are submitted.
- Automated code checking: Review billing codes for potential errors and inconsistencies before claim submission.
- Claims management: Prepare, submit, and track insurance claims throughout the reimbursement process.
- Detailed reporting: Monitor denials, payments, outstanding claims, and overall revenue cycle performance.
Visolve Medical Billing Module Integrations
Visolve Medical Billing Module supports connections with EHR, practice management, clearinghouse, and other healthcare systems. These integrations help synchronize patient, clinical, and billing data while reducing duplicate entry across workflows.
Pros and Cons
Pros:
- Robust feature set for comprehensive billing management
- Flexible to fit diverse workflows
- High interoperability with various systems
Cons:
- Limited online resources for user support
- No free trial available
Verana Health is a healthcare data and analytics company that uses real-world clinical data to support quality improvement, research, life sciences, and specialty practice performance. It is not a traditional medical billing platform.
Who Is Verana Health Best For?
Verana Health works well for specialty practices, medical societies, and life sciences organizations that need real-world data, quality reporting, and clinical performance insights.
Why I Picked Verana Health
I picked Verana Health because its analytics and quality measurement tools can help specialty practices better understand clinical performance and value-based care requirements. Its dashboards and advisory services may also support MIPS participation by helping clinicians monitor quality measures and identify reporting opportunities. Although it does not replace dedicated billing software, these insights can indirectly support reimbursement planning and practice performance.
Verana Health Key Features
- Quality measure dashboards: Monitor clinical performance metrics and track progress against relevant quality measures.
- MIPS advisory support: Help clinicians understand reporting requirements and navigate Merit-based Incentive Payment System workflows.
- Real-world data analytics: Analyze de-identified clinical data to support research, care improvement, and life sciences initiatives.
- Specialty data registries: Organize and evaluate clinical information from participating specialty practices and medical societies.
Verana Health Integrations
Verana Health primarily works with participating EHR systems, specialty data registries, and clinical data networks to collect and analyze real-world information. Public details about direct billing, accounting, or practice management integrations are limited.
Pros and Cons
Pros:
- AI-powered insights engine enhances data usability.
- Supports ophthalmology, neurology, urology specialties.
- Access to 90M+ real-world patient data records.
Cons:
- Limited suitability for general practices.
- Not full-feature medical billing software.
Other AI Medical Billing Software Tools
- Paystri
For flexible patient payment plans
- Billiyo
For home health agencies and therapy providers
- PulsePro Practice Management
For complete revenue cycle management
- Cortex EDI
For managing the entire revenue cycle
- TotalMD
For scalable solutions from single users to large networks
- Mobile Mediclaim
For on-the-go billing and claims
- Easy Billing Professional
For customizable invoicing and payment tracking
- PatientClick Suite
For automated claim submissions
- AMS Ultra Charts
For complex billing and invoicing
- expEDlum Medical Billing Software
For secure cloud hosting
How I Evaluate AI Medical Billing Software
Every tool on this list needs to show that its AI goes beyond buzzwords—actually reducing manual work in coding, claims, or denials. I split my evaluation into two layers: core functionality every platform must deliver to qualify and differentiating factors that separate one vendor from another.
Core Functionality (Table Stakes for This List)
When I'm selecting tools for my list, I rank each one on a scale from 0 (does not offer the functionality) to 5 (excels in this area) for each core functionality listed below. Then, I calculate the tool's total score into a percentage. Each tool needs to achieve a minimum total score of 65% to be considered for inclusion.
- Claims Management: I look for full lifecycle claim handling, from scrubbing and electronic submission to real-time status tracking across multiple clearinghouses.
- Medical Coding Support: Each platform should support ICD-10, CPT, and HCPCS with built-in validation, so coders catch modifier issues before claims go out the door.
- Eligibility Verification: I evaluate whether the tool checks patient coverage in real time or in batch runs before appointments, surfacing benefit details and flagging lapses early.
- Patient Billing & Payments: The platform should generate e-statements and offer flexible collection options like payment plans or card-on-file, reducing the back-and-forth with patients.
- Denial Management & ERA Posting: I check how each tool handles automated ERA posting, denial categorization, and rework queues to keep A/R from aging out.
- HIPAA Compliance: Every tool needs to demonstrate HIPAA-compliant data handling with audit trails, role-based access, and a signed BAA at minimum.
Once I have a list of tools that meet the criteria, I consider what sets each platform apart.
Differentiating Factors (What Sets Vendors Apart)
Here's how I compare and contrast different vendors:
Standout Features
Reporting and analytics matter here. I look for dashboards that track A/R aging, denial trends, and payer-level performance so your team can spot revenue leaks before they grow. Clearinghouse flexibility is another key differentiator—some platforms lock you into one clearinghouse, while others support multiple connections or bundle their own. I also evaluate specialty-specific workflows, like pre-built code sets and fee schedules for mental health or DME billing, which cut setup time and reduce coding mistakes out of the gate.
Beyond Features
EHR integration is a big one. I check whether a platform offers bi-directional sync with systems like Epic or athenahealth via HL7/FHIR. Manual data re-entry creates errors and slows billing cycles. Service model fit also matters. Some teams want standalone software for in-house billers, while others need full-service RCM with SLAs and follow-up transparency. I also evaluate pricing structure, looking at whether costs scale by provider count, claim volume, or percentage of collections as your practice grows.
How to Choose AI Medical Billing Software
It’s easy to get bogged down in long feature lists and complex pricing structures. To help you stay focused as you work through your unique software selection process, here’s a checklist of factors to keep in mind:
| Factor | What to Consider |
| Scalability | Will the solution support your claim volumes as your practice grows or adds providers and locations? |
| Integrations | Can you connect billing software directly to your EHR, PM, or accounting platform without extra workarounds? |
| Customizability | Do you need specialty-specific templates, billing rules, or workflow tweaks, or will an out-of-the-box system suffice? |
| Ease of use | Will your billers, coders, and admin staff pick it up fast, or is there a long learning curve? |
| Implementation and onboarding | How much time and internal effort will it take to import data, train your team, and get fully up and running? |
| Cost | Does pricing fit your budget model—per provider, per claim, or percent of collections—without hidden fees? |
| Security safeguards | Does the vendor provide HIPAA-grade encryption, audit logs, access controls, and signed BAAs? |
| Support availability | Will you have quick access to help during errors, payer updates, or downtime, and through which channels? |
What Is AI Medical Billing Software?
AI medical billing software uses artificial intelligence to automate complex billing tasks, including coding, claim scrubbing, submission, and payment posting. These platforms help billing teams reduce manual errors, speed up insurance workflows, and stay compliant with revenue cycle regulations. Practices use AI medical billing software to handle claims, denial management, and patient invoicing with greater efficiency and accuracy.
Features of AI Medical Billing Software
When selecting AI medical billing software, keep an eye out for the following key features:
- Claims management: Automates claim creation, scrubbing, electronic submission, and payer tracking to reduce errors and administrative workload.
- Medical coding assistance: Offers real-time coding suggestions, code set updates, and error alerts to ensure claims comply with ICD-10, CPT, and HCPCS standards.
- Eligibility verification: Instantly checks patient insurance coverage—either before or at the time of service—so you can prevent unpaid claims due to ineligible coverage.
- Denial management: Identifies, categorizes, and routes denied claims for rework, while surfacing root causes and suggesting actions to improve first-pass acceptance.
- ERA posting: Automatically posts electronic remittance advice, matches payments to claims, and flags discrepancies for follow-up.
- Patient billing and payments: Generates e-statements, supports online payments, sends automated reminders, and manages payment plans to increase patient collection rates.
- User access controls: Sets role-based permissions to ensure compliance and protect sensitive billing and patient data from unauthorized access.
- Analytics and reporting: Provides dashboards with A/R metrics, denial trends, and payer performance, allowing teams to monitor revenue health and quickly address issues.
- Audit trails: Tracks every user action, claim edit, and payment posting for regulation compliance and easier troubleshooting during audits.
- Integration capabilities: Connects with EHRs, practice management tools, and clearinghouses to ensure consistent, error-free information flow throughout the revenue cycle.
Benefits of AI Medical Billing Software
Implementing AI medical billing software provides several benefits for your team and your business. Here are a few you can look forward to:
- Fewer claim denials: Automated claim scrubbing, coding validation, and eligibility checks catch errors before submission and reduce rejected claims.
- Faster payment cycles: Real-time submission, ERA posting, and instant payer status updates help payments arrive sooner without manual follow-up.
- Less manual data entry: Integration with EHRs and intelligent automation removes redundant paperwork and reduces the risk of human error.
- Better compliance: Built-in HIPAA safeguards, audit trails, and automated workflows help practices maintain regulatory and data security standards.
- Clearer financial insights: Custom dashboards and reporting tools give your team ongoing visibility into A/R, collection rates, and denial trends.
- Improved patient collections: Features like e-statements, text-to-pay, and flexible online payment portals make it easier for patients to pay balances.
- Increased staff productivity: AI-driven workflows free up billers and coders to focus on complex tasks instead of repetitive administrative work.
Costs and Pricing of AI Medical Billing Software
Selecting AI medical billing software requires an understanding of the various pricing models and plans available. Costs vary based on features, team size, add-ons, and more. The table below summarizes common plans, their average prices, and typical features included in AI medical billing software solutions:
Plan Comparison Table for AI Medical Billing Software
| Plan Type | Average Price | Common Features |
| Free Plan | $0 | Supports basic claim entry, offers limited reporting, allows manual payment recording, and includes email support. |
| Personal Plan | $20-$60/user/month | Provides electronic claim submission, eligibility verification, standard reporting tools, and phone support. |
| Business Plan | $75-$200/user/month | Adds AI-assisted claim scrubbing, ERA posting, batch eligibility checks, integration with EHRs, and payment plans. |
| Enterprise Plan | $250+/user/month | Includes advanced automation, predictive analytics, custom workflows, dedicated onboarding, and priority support. |
AI Medical Billing Software FAQs
Here are some answers to common questions about AI medical billing software:
How does AI improve accuracy in medical billing?
AI checks claims for coding errors, missing details, and eligibility problems before submission. This proactive review reduces denials and ensures claims are sent correctly the first time, saving your team time and reducing write-offs.
Can AI medical billing software integrate with my current EHR?
Yes, most AI medical billing software offers integration with leading EHRs through APIs or standards like HL7 and FHIR. Check if your vendor provides real-time, two-way syncing to avoid manual entry and data mismatches.
What should I look for when evaluating security in AI medical billing software?
Look for HIPAA compliance, encrypted data storage and transfer, granular access controls, and regular security audits. Signed BAAs and SOC 2 or HITRUST certifications also demonstrate a vendor’s commitment to protecting patient data.
How long does it take to implement AI medical billing software?
Implementation can take anywhere from a few days to several weeks, depending on data migration needs, team training, EHR integrations, and workflow customization. Discuss onboarding resources and go-live timelines with your vendor.
Is AI medical billing software suitable for all practice sizes?
Yes, AI medical billing software can work for small clinics, multi-location groups, and large hospital systems. Make sure the plan you choose fits your claim volume, specialty needs, and staff size to get the most value.
