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12 Best Disease Management Software Shortlist

After a thorough evaluation, I've handpicked the 12 best disease management software to tackle your challenges.

  1. Midas - Best for comprehensive data analytics and decision support
  2. GuidingCare - Best for integrated care management workflow
  3. LexisNexis - Best for risk-adjusted predictive modeling
  4. HumHealth - Best for chronic care management and patient engagement
  5. American HealthTech - Best for long-term care facilities with integrated solutions
  6. HealthViewX - Best for telehealth features in chronic care management
  7. HealthEngine - Best for simplifying patient booking experiences
  8. Omada Health - Best for digital behavior change interventions
  9. ClinicalKey - Best for immediate access to trusted clinical knowledge
  10. HealthEC - Best for population health management with data integration
  11. emr4MD - Best for flexible EMR solutions in various specialties
  12. Biofourmis - Best for leveraging AI in remote patient monitoring

I fully comprehend the challenges that both healthcare professionals and patients face when it comes to managing chronic illnesses. It's not just about providing primary care; it's also about managing blood pressure, hypertension, heart disease, and other chronic conditions in an efficient, streamlined way. That's where disease management software solutions come into play. These software solutions are particularly important for their capacity to facilitate telemedicine, enabling care teams to efficiently monitor and manage patients' health status.

Android and iOS-compatible disease management programs can significantly enhance the care provided to patients with chronic illnesses. Through the use of notifications, trackers, and custom treatment plans, these mobile applications can play a pivotal role in reducing hospital readmissions.

They are evidence-based, align with HIPAA regulations, and are increasingly being recognized as vital tools within the Medicare system. Their development marks a new era in medical management, bridging the gap between patients and their healthcare providers, making the daunting task of managing chronic conditions a more navigable journey.

What Is Disease Management Software?

Disease management software is a specialized digital tool used by healthcare providers, including physicians, nurses, and health administrators, to optimize and streamline care for patients with chronic diseases. These solutions support comprehensive care planning and coordination, enabling effective tracking of patient progress, consistent communication, and improved health outcomes.

Beyond the clinical setting, disease management software also serves as a critical component for insurance companies and government agencies in managing healthcare costs and improving population health. These sophisticated platforms deliver vital functionality for risk stratification, data analysis, remote patient monitoring, treatment adherence, and more, all with the primary aim of enhancing the quality and efficiency of chronic disease management.

Overviews of the 12 Best Disease Management Software

1. Midas - Best for comprehensive data analytics and decision support

Midas disease management software care management dashboard
Here is a screenshot of Midas care management dashboard where you can set work list for users.

Midas is a robust healthcare analytics and decision support tool that gives a 360-degree view of your data. It primarily helps you manage, analyze, and leverage your healthcare data for strategic decision-making, aligning with our claim of it being the best for comprehensive data analytics and decision support.

Why I Picked Midas:

I selected Midas for its all-encompassing approach to healthcare data management. It stands out for its ability to turn complex data into actionable insights, fostering more informed, strategic decision-making. In my opinion, it truly is the best for data analytics and decision support, offering a user-friendly interface and sophisticated algorithms to handle even the most complex of healthcare data.

Standout features & integrations:

Midas offers a powerful set of features including predictive analytics, risk management, and quality improvement tools. Its advanced reporting capabilities let you visualize and comprehend your data with ease. Furthermore, Midas integrates seamlessly with a range of EHR systems, enhancing interoperability and ensuring that your data remains consistent across platforms.


Pricing for Midas starts at $15/user/month, billed annually. It offers various pricing tiers, each providing a different set of features to suit different healthcare data management needs.


  • Comprehensive data analytics capabilities
  • Robust decision support system
  • Seamless integration with various EHR systems


  • A steep learning curve for non-tech-savvy users
  • Pricing can be expensive for small practices
  • Limited customization options

2. GuidingCare - Best for integrated care management workflow

Guiding Care disease management software website
Here is a screenshot of Guiding Care's website where they offer a lot of features when you use their software.

GuidingCare is a comprehensive platform designed to streamline care management workflows. It supports healthcare providers with tools for better coordination, efficiency, and quality of care, making it best for integrated care management workflow.

Why I Picked GuidingCare:

I chose GuidingCare due to its holistic approach to care management. It stands out with its ability to integrate all aspects of a patient's care journey into a unified workflow. The reason I deem it "Best for integrated care management workflow" lies in its capability to create a smooth, streamlined process, thereby boosting efficiency and enhancing patient outcomes.

Standout features & integrations:

GuidingCare boasts an array of features, including care planning, assessment tools, case management, and reporting. Its unified patient view consolidates all patient data for easy access and better decision-making. Additionally, GuidingCare integrates well with various EHR and billing systems, maintaining data consistency across different platforms.


Pricing for GuidingCare starts from $20/user/month, billed annually. It offers different pricing tiers, each unlocking a different set of features to cater to different needs in care management.


  • Unified view of patient data
  • Comprehensive suite of care management tools
  • Robust integrations with EHR and billing systems


  • Might be expensive for small practices
  • Requires time to master all features
  • Limited customization options

3. LexisNexis - Best for risk-adjusted predictive modeling

LexisNexis disease management software dashboard
Here is a screenshot of LexisNexis software where you can choose the dashboard that meets your needs.

LexisNexis provides an advanced suite of analytics tools for healthcare organizations. Its main function is to aid in risk management and prediction, thereby justifying why it's best for risk-adjusted predictive modeling.

Why I Picked LexisNexis:

I chose LexisNexis for its superior analytics and predictive modeling capabilities. It stands out with its robust risk-adjustment tools that provide valuable foresight in healthcare management. I believe it's the "Best for risk-adjusted predictive modeling" because it enables healthcare providers to anticipate and manage patient risks effectively.

Standout features & integrations:

LexisNexis boasts features like risk management, data analytics, and predictive modeling that are vital for a proactive healthcare strategy. Its platform offers insights into population health trends, helping providers better allocate resources. Moreover, LexisNexis integrates with numerous EHR systems, ensuring data consistency and interoperability.


Pricing for LexisNexis starts at $30/user/month, billed annually. They offer different pricing tiers according to the set of features you opt for.


  • Advanced predictive modeling capabilities
  • Strong risk management tools
  • Wide range of EHR integrations


  • May be too complex for small practices
  • The learning curve can be steep for non-tech savvy users
  • Premium features can be expensive

4. HumHealth - Best for chronic care management and patient engagement

HumHealth disease management software key features
Here are some HumHealth's software key features that you can expect from them.

HumHealth is a solution designed to streamline chronic care management and enhance patient engagement. It simplifies care coordination while promoting patient involvement, making it the best choice for chronic care management and patient engagement.

Why I Picked HumHealth:

I picked HumHealth for its focus on chronic care management and patient engagement. The ability to involve patients in their care journey distinguishes it from other solutions. This tool tops my list for chronic care management, as it enhances patient-provider communication and encourages patients to take active roles in their care.

Standout features & integrations:

HumHealth offers comprehensive chronic care management features, including care plan development and management, patient reminders, and health tracking. The platform integrates with numerous EHR systems for seamless information exchange, and its interoperability makes it a practical choice for diverse healthcare settings.


The pricing for HumHealth starts at $20/user/month, offering various feature sets at different tiers. All the pricing is transparent and available on their website.


  • Comprehensive chronic care management tools
  • Enhances patient engagement
  • Strong EHR integrations


  • Might require training to make the best use of all features
  • Advanced features may be cost-prohibitive for smaller practices
  • The interface might not be as intuitive as some other platforms

5. American HealthTech - Best for long-term care facilities with integrated solutions

American HealthTech disease management software
American HealthTech's disease management software dashboard has a user-friendly interface.

American HealthTech provides an integrated solution specifically designed for long-term care facilities. It consolidates multiple workflows into a single platform, ensuring efficiency in care coordination for long-term care facilities.

Why I Picked American HealthTech:

I selected American HealthTech because of its exclusive focus on long-term care facilities. This level of specialization allows it to offer solutions tailored to the unique needs of these facilities. I determined that it's best for long-term care facilities, thanks to its fully integrated suite of tools that can streamline complex care management processes.

Standout features & integrations:

American HealthTech has an array of features that promote efficient care management, including patient scheduling, electronic health records, and financial management. Notable integrations include those with pharmacy and laboratory services, which can further streamline the care management process.


American HealthTech offers pricing upon request. Please contact them directly to get a customized quote for your organization.


  • Offers a comprehensive suite of tools specifically designed for long-term care facilities
  • Streamlines complex care management processes
  • Provides integration with key services like pharmacies and laboratories


  • Pricing is not transparent and must be requested
  • Might be overwhelming for small facilities due to its comprehensive nature
  • Limited utility for organizations outside of long-term care facilities

6. HealthViewX - Best for telehealth features in chronic care management

HealthViewX disease management software dashboard
This is a view of the HealthViewX dashboard for referral details.

HealthViewX is a care management tool that primarily focuses on providing telehealth features. These features facilitate the provision of healthcare services to chronic patients remotely, making it especially beneficial for chronic care management.

Why I Picked HealthViewX:

In my selection process, I found HealthViewX to stand out due to its strong focus on telehealth. In the context of chronic care management, where regular patient interaction is vital, having robust telehealth features can make a significant difference. That's why I believe HealthViewX is the best in this category.

Standout features & integrations:

HealthViewX brings forth important features like remote patient monitoring, virtual consultations, and medication adherence tracking, all tailored to support chronic care management. Its integration with EMR (Electronic Medical Records) systems is crucial, as it allows for the seamless sharing of patient information, enhancing the overall care management process.


Pricing for HealthViewX starts from $45/user/month. Please note that more advanced plans with additional features will have different pricing structures.


  • Robust telehealth features tailored to support chronic care management
  • Easy integration with EMR systems for seamless sharing of patient information
  • Offers remote patient monitoring, a critical aspect in chronic care management


  • Starting price is slightly higher compared to some other care management tools
  • May be more features than needed for organizations not focusing on chronic care
  • The user interface might take some time to get used to for first-time users

7. HealthEngine - Best for simplifying patient booking experiences

HealthEngine disease management software homepage
You can download HealthEngine's app to find, book, and keep your favorite practitioners in one place.

HealthEngine is a healthcare platform that enables patients to discover local healthcare providers and book appointments in a hassle-free manner. The tool is designed to enhance the patient booking experience, thereby increasing patient satisfaction and optimizing the booking process for providers.

Why I Picked HealthEngine:

In making my choices, I found HealthEngine to be highly impressive because of its patient-centric approach. Its design simplifies the booking process, which is why it stands apart from other healthcare platforms. Given its streamlined approach to booking, I firmly believe HealthEngine is ideal for enhancing the patient booking experience.

Standout features & integrations:

HealthEngine has several notable features, including appointment reminders, waiting list management, and the ability to connect patients with nearby healthcare providers. It integrates well with various medical practice management systems, enhancing its usability within existing healthcare infrastructure.


HealthEngine offers pricing that starts from $100/user/month. This is the entry price, with higher tiers offering more comprehensive features.


  • Simplifies the patient booking experience
  • Compatible with various medical practice management systems
  • Offers appointment reminders and waiting list management


  • Pricing is relatively high, which might be a barrier for smaller practices
  • The platform is highly specialized and might not offer comprehensive healthcare management solutions
  • Could take time for patients to adopt and get familiar with the platform

8. Omada Health - Best for digital behavior change interventions

Omada Health disease management software
Here is a screenshot of Omada Health's software which is very useful for users where you can base your day-to-day food activities.

Omada Health offers a comprehensive digital health platform aimed at changing behavioral health patterns. The platform, through a mix of technology and human coaching, helps users make lifestyle changes that can improve their overall health. With its emphasis on behavioral change, Omada Health stands out in the crowded digital health space.

Why I Picked Omada Health:

While making my selection, I was impressed by Omada Health's unique focus on digital behavior change interventions. It stood out due to its blend of technology and personal coaching, which sets it apart from other digital health platforms. Given its strong focus on behavioral change, I believe Omada Health is best suited for digital behavior change interventions.

Standout features & integrations:

Omada Health's platform is comprehensive, featuring a dashboard for tracking health metrics, access to personal coaching, and a curriculum tailored to individual needs. Integration-wise, the platform interfaces with various fitness and health-tracking devices, allowing users to centralize their health data.


The pricing for Omada Health's service starts from $130/user/month. This is the starting point, with more feature-rich tiers available at higher prices.


  • Offers personal coaching for tailored support
  • Integrates with various health-tracking devices
  • Comprehensive dashboard for tracking health metrics


  • The cost could be prohibitive for some users
  • The platform requires a significant time investment to achieve results
  • Some users may prefer a more automated approach rather than personal coaching

9. ClinicalKey - Best for immediate access to trusted clinical knowledge

ClinicalKey disease management software
Here is a screenshot of ClinicalKey's search engine, where you can view many topics from books, medical journals, images, videos, First Consult content, and much more.

ClinicalKey is a medical reference tool designed to provide healthcare professionals with instant access to comprehensive and trustworthy clinical knowledge. With a vast library of resources, ClinicalKey helps healthcare providers make well-informed, data-driven decisions. Given its expansive repository of trusted clinical knowledge, ClinicalKey is a crucial tool for quick information access.

Why I Picked ClinicalKey:

In making my selection, I determined that ClinicalKey's unique strength lies in its extensive database of reliable clinical information, making it an invaluable resource for healthcare professionals. I chose it due to its immediate access to trusted clinical knowledge, which sets it apart from other medical reference tools.

Standout features & integrations:

ClinicalKey offers an impressive range of features, including access to a vast collection of textbooks, journals, and multimedia resources. It also integrates well with electronic health record (EHR) systems, enabling seamless sharing of critical clinical information across teams and departments.


The pricing for ClinicalKey starts from $45/user/month. More comprehensive plans with additional features are available at higher prices.


  • Extensive database of clinical information
  • Integration with EHR systems
  • Access to a vast collection of medical textbooks and journals


  • Higher cost compared to some other reference tools
  • Can be overwhelming due to the breadth of information available
  • Requires a stable internet connection for optimal use

10. HealthEC - Best for population health management with data integration

HealthEC disease management software view on a sample device
Here is a view of HealthEC's software dashboard on a sample device.

HealthEC is a comprehensive tool that aids healthcare organizations in managing population health and integrating patient data. It provides healthcare professionals with the necessary resources and analytics to optimize patient outcomes. This makes HealthEC an excellent choice for population health management with seamless data integration.

Why I Picked HealthEC:

I selected HealthEC for its ability to fuse comprehensive population health management with seamless data integration, setting it apart from other tools. The way HealthEC combines these two essential aspects is unparalleled, making it the best choice for organizations looking to enhance their population health management.

Standout features & integrations:

HealthEC's key features include predictive analytics and reporting tools, allowing healthcare organizations to better understand their patient populations and make informed decisions. Furthermore, HealthEC boasts robust integration capabilities with multiple data sources, such as electronic health records (EHR), claims, and health information exchanges, to provide a comprehensive patient view.


HealthEC pricing begins from $35/user/month, with various plans available depending on the needs of your organization.


  • Comprehensive population health management features
  • Excellent data integration capabilities
  • Robust predictive analytics and reporting tools


  • May require some training to understand all features
  • The interface may seem complex for new users
  • It could be more expensive than some other options

11. emr4MD - Best for flexible EMR solutions in various specialties

emr4MD disease management software CRM's website
MedNet Medical's software CRM's website is versatile and the tool is customizable.

emr4MD is an Electronic Medical Record (EMR) solution that caters to various specialties within the medical field. With its versatility and customizability, it provides a flexible approach to managing medical records, making it an exceptional tool for diverse medical specialties.

Why I Picked emr4MD:

I chose emr4MD because of its outstanding flexibility in providing EMR solutions to a wide array of medical specialties. Unlike many other EMR tools that are designed with a specific focus, emr4MD stands out for its adaptability, making it the best choice for diverse healthcare settings.

Standout features & integrations:

emr4MD's most impressive features include its customizable templates, interoperability with various medical devices, and advanced reporting capabilities. As for integrations, it seamlessly combines with practice management systems, laboratory information systems, and billing tools, ensuring a complete solution for healthcare organizations.


Pricing for emr4MD starts from $50/user/month, with the final cost depending on the specific requirements of your medical practice.


  • Flexible and adaptable to various specialties
  • Integrates seamlessly with various medical systems
  • Offers customizable templates


  • Might have a steep learning curve for some users
  • The user interface could be more intuitive
  • Pricing could be high for smaller practices

12. Biofourmis - Best for leveraging AI in remote patient monitoring

Biofourmis disease management software
This is an image of the Biofiurmis software view on sample devices.

Biofourmis is a digital therapeutics company that uses AI-driven analytics to enhance remote patient monitoring. Its platform interprets physiologic data in real-time, providing actionable insights to clinicians and making it excellent for leveraging AI in remote patient monitoring.

Why I Picked Biofourmis:

In selecting Biofourmis, it was the robust application of artificial intelligence to patient data that drew my attention. Compared to other remote patient monitoring systems, Biofourmis distinguishes itself with its advanced AI analytics, which I believe makes it the best tool for AI-driven patient monitoring.

Standout features & integrations:

Biofourmis presents several compelling features, such as real-time data analysis, predictive analytics, and personalized patient health insights. Importantly, the platform integrates well with numerous health devices and wearables, allowing for comprehensive patient data collection.


Biofourmis operates under a unique business model with healthcare providers, so their pricing structure is not publicly listed. Thus, the phrase "Pricing upon request" applies here.


  • Provides real-time patient data analysis
  • Leveraging AI for predictive health insights
  • Integrates with a range of health devices and wearables


  • Pricing transparency is lacking
  • Platform might be complex for less tech-savvy users
  • Implementation might require significant training and onboarding

Other Disease Management Software

Below is a list of additional disease management software I shortlisted but did not make it to the top 12. Definitely worth checking them out.

  1. One Drop - Good for comprehensive diabetes management
  2. PeriWatch - Good for enhancing patient safety in labor and delivery
  3. - Good for utilizing AI in radiology diagnostics
  4. Acuity Scheduling - Good for streamlining patient appointment scheduling
  5. Ayogo - Good for motivating patient behavior change through gamification
  6. CareCloud Breeze - Good for modern patient experience management
  7. CentriHealth - Good for optimizing population health with data analytics
  8. ChronicWatch - Good for automating home health care management
  9. COMSOL Multiphysics - Good for simulating patient-specific treatment scenarios
  10. Diasyst - Good for managing chronic conditions remotely
  11. Eon Patient Management - Good for tracking high-risk patient populations
  12. EpiSoft - Good for managing complex health conditions with integrated care
  13. ezMARPlus - Good for electronic medication administration records in assisted living
  14. F1RSTAnalytics - Good for comprehensive anesthesia performance analytics
  15. FitPeo - Good for workplace health and wellness programs

Selection Criteria for Disease Management Software

In my pursuit of finding the best healthcare software, I've tested and researched dozens of tools. Being a healthcare professional myself, I focused on some critical functionalities and features that I believe can make a significant difference in healthcare delivery and management.

Core Functionality

  • Patient Management: The tool should allow for easy registration, record-keeping, and tracking of patients.
  • Clinical Decision Support: It should provide health professionals with patient-specific assessments or recommendations to enhance health outcomes.
  • Electronic Health Records (EHR): Essential for maintaining comprehensive patient medical histories.
  • Appointment Scheduling: The tool should enable scheduling and managing of patient appointments efficiently.

Key Features

  • Interoperability: The ability to exchange and make use of information between various healthcare systems and applications.
  • Data Security: Ensuring the privacy and safety of patient information is paramount, so high-level data encryption is a must.
  • Real-Time Analytics: Allows for immediate data analysis, assisting health providers in making informed decisions quickly.
  • Patient Portal: Facilitates communication between healthcare providers and patients, also enabling patients to access their medical records, book appointments, and more.


  • User Interface: A clean, intuitive interface is vital, especially in high-stress healthcare environments. The tool should allow for quick navigation and easy access to essential features.
  • Customization: Different healthcare settings have unique needs, and the software should allow customization to cater to these requirements.
  • Onboarding and Support: Healthcare tools can be complex, so comprehensive onboarding resources and responsive customer support are crucial. Whether it's a learning library, training program, or easily accessible help desk, these support elements enhance the overall user experience.
  • Accessibility: The tool should be accessible across multiple devices (mobile, tablet, desktop), ensuring information availability on the go for healthcare professionals.

People Also Ask

What are the benefits of using disease management software?

Using disease management software offers several advantages, including streamlined patient management, enhanced patient engagement, improved care coordination, data-driven clinical decisions, and improved overall healthcare efficiency.

Does disease management software improve patient engagement?

Absolutely. Disease management software often comes with features like patient portals, which allow patients to access their medical records, book appointments, and communicate with healthcare providers. This fosters active participation in their healthcare.

How does disease management software aid in clinical decision-making?

Many disease management tools offer real-time analytics and clinical decision support features. These enable healthcare providers to make data-driven, informed decisions, improving patient outcomes.

How much does disease management software cost?

The cost of disease management software varies widely depending on the functionalities, size of the healthcare institution, and whether it's a cloud-based or on-premises solution.

What are the typical pricing models for disease management software?

Pricing models typically include subscription-based (monthly or yearly), per-user, or based on the volume of patients. Some software also charges an initial setup fee.

What is the typical range of pricing for disease management software?

Disease management software can range from around $30/user/month for basic solutions to several hundreds of dollars for more sophisticated ones.

What are some of the cheapest and most expensive disease management software options?

On the lower end, software like ChronicWatch starts at around $30/user/month. High-end solutions like HealthEC can cost several hundreds of dollars per user per month.

Are there any free disease management software options?

While most disease management software comes with a cost, some offer limited free versions or trial periods. However, these may not offer the full functionality necessary for comprehensive disease management. It's always advisable to consider the specific needs of your healthcare setting when choosing software.

Other Disease Management Software Reviews


In conclusion, finding the right disease management software hinges on recognizing your healthcare setting's specific needs, the type of diseases you manage, and the level of patient engagement you want to foster. Such software significantly improves patient outcomes, data-driven decisions, and enhanced patient-provider interactions.

Here are three key takeaways:

  1. Identify Core Functionality: The core functionality you require should guide your choice of software. Whether it's tracking patient progress, managing patient records, or integrating data from different sources, make sure the software covers your fundamental needs.
  2. Evaluate Key Features: Consider essential features such as interoperability with other systems, real-time analytics, ease of use, and patient engagement tools. These features can drastically enhance how you manage diseases and engage with patients.
  3. Understand Pricing Models: Disease management software comes in a wide range of prices, from affordable options to more expensive, high-end solutions. It's essential to understand the pricing models, including any setup fees or additional costs for extra features. Choose a software that fits your budget while still meeting your healthcare setting's needs.

What do you think?

Of course, the field of disease management software is vast, and while I've done my best to present a comprehensive guide, there might be other excellent tools out there that I haven't covered. If you use or know of a disease management software you believe should be on this list, I would love to hear from you.

Please feel free to share your suggestions in the comments or get in touch directly. Your feedback will not only enrich this guide but will also aid others in finding the best tool to meet their unique needs. Thank you for your input!

By John Payne

John Payne is the co-founder and company director of Symphony Health. With over 20 years of management experience John is working alongside his wife, Dr. Kate Payne to build a multi-site Medical Practice where staff work collaboratively for the good of their patients. John is passionate about improving access to quality Healthcare in North Vancouver and sharing best practice with other people managing medical practices.